Update on the Use of SSRIs and SNRIs with Children and Adolescents in Clinical PracticeUploader: Kazit 1 years ago Subscribe 8
In one trial, there was no statistically significant difference in suicidality with venlafaxine compared to SSRIs, although both cardiovascular and dermatological adverse effect rates were higher than with SSRIs Brent et al. Some studies may have failed to demonstrate significant efficacy using primary outcomes but when secondary outcomes are analyzed they suggest significant differentiation from placebo or tricyclic comparators Keller et al. MMRM, mixed effects model repeated measures. Other important people in your child's life can help by paying attention as well e. Treatment-emergent suicidal ideation and behavior are areas of concern in pediatric MDD patients, and suicidal ideation and behavior were closely monitored and solicited at every visit using the C-SSRS in this study.